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A Buyer's Guide to the 8 Strongest CBD Oils You Can Buy Online in 2021

Could a higher concentration of CBD help you? See which brands offer the strongest CBD oil tinctures.
Each product we feature has been independently selected and reviewed by our editorial team. If you make a purchase using the links included, we may earn commission.

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Strongest CBD oils at a glance:

When it comes to CBD oils for pain relief and relaxation, weak formulas sometimes don't contain enough cannabinoids for you to feel the wellness effects of CBD. You may experience better symptom relief by choosing a high-potency CBD oil instead.

Cannabinoids are the active compounds in the hemp plant that interact with your endocannabinoid system to help regulate numerous systems in your body. Cannabidiol (CBD) is a cannabinoid valued for therapeutic benefits that may help relieve chronic pain, reduce anxiety, and more.

If you need serious relief, consider a more potent CBD oil tincture with a higher amount of CBD per serving. The following brands offer some of the strongest CBD oils on the market today. Here are the CBD products that may provide serious relief.

Our top choices for high-potency CBD oils:

We examined research on the safety and efficacy of high CBD concentrations and compared popular CBD brands to compile this list of the eight strongest CBD oils for 2021. Below, you can read about each product to learn more about its CBD concentration, ingredients list, and use instructions to determine which ones may be the best fit for your health goals.

Here are the specific factors we used to create our list:

  • Concentration
  • Third-party lab testing
  • Hemp source
  • Price
  • Customer reviews

Complete reviews of our top picks for strong CBD oils

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Credit: thecbdistillery.com

Strongest CBD Oil: CBDistillery Full-Spectrum CBD Oil

Buy It
  • Type of CBD: Full-spectrum
  • Potency: 167 milligrams of CBD per 1 milliliter dropper
  • COA: Available online
  • Price: $$
  • Customer review: "Love the CBD 5000 milligram product. Works amazing! Will definitely purchase again!"

This 5,000 milligram CBD oil from CBDistillery is the most potent product on our list. It contains 167 milligrams of full-spectrum hemp extract in every one milliliter dropper for a high-strength and high-quality CBD oil. All of the brand's CBD oil products are third-party lab tested by ACS Laboratory and offer transparent ingredient lists and certificates of analysis. Choose the 5,000 milligram option if you're looking for a CBD oil that may provide additional relief from chronic pain or help managing anxiety.

Best Full-Spectrum: Spruce Lab Grade CBD Oil

Buy It
  • Type of CBD: Full-spectrum
  • Potency: 80 milligrams of CBD per 1 milliliter dropper
  • COA: Available online
  • Price: $$$
  • Customer review: "This stuff works wonders! It's high quality, take it from an experienced user. I am completely satisfied with Spruce's 2400 milligram CBD oil. I'll be buying more!"

Spruce specializes in high-potency full-spectrum CBD oil that contains a unique terpene profile. This helps create a stronger entourage effect from the interaction of the cannabinoids, essential oils, terpenes, and flavonoids. Spruce offers two different carrier oils for its full-spectrum CBD: organic hemp seed oil and organic coconut MCT oil. Both are vegan, gluten-free, and free of artificial flavors, preservatives, and sweeteners. Spruce CBD is tested by ProVerde Labs, ACS Laboratory, and CannaBusiness Labs.

Credit: medterracbd.com

Best CBD Isolate: Medterra Isolate CBD Oil

Buy It
  • Type of CBD: CBD isolate
  • Potency: 33 or 100 milligrams of CBD per 1 milliliter dropper
  • COA: Available online
  • Price: $
  • Customer review: "This stuff is the most reasonably priced CBD I've found, has trustworthy testing, and tastes the cleanest of all the ones I've tried."

It's hard to beat Medterra's CBD isolate tincture if you're looking for pure CBD without THC. The brand's CO2 extraction process removes 100% of the THC, so you're left with a 99.6% pure CBD extract blended with MCT oil for easier absorption. At 100 milligrams of CBD per one milliliter dropper, the 3,000 milligram concentration is the strongest THC-free option on our list. Medterra uses hemp grown according to the Kentucky Department of Agriculture organic farming practice requirements, and all products are tested by third-party labs including Sante Laboratories and Green Scientific Labs.

Credit: rrmeds.com

Best Value: R+R Medicinals CBD Tincture

Buy It
  • Type of CBD: Full-spectrum
  • Potency: 41.67 milligrams of CBD per 1 milliliter dropper
  • COA: Available online
  • Price: $
  • Customer review: "It is a strong flavor, but works great! From the first dose, I slept all night without waking up. I use this product to help with insomnia and depression/anxiety relief and it works wonderfully!"

This full-spectrum CBD oil from R+R Medicinals offers a phytonutrient-rich formula for pain relief and relaxation. Each serving contains 41.7 milligrams of organic CBD and nearly five milligrams of minor cannabinoids and terpenes for a more potent effect. If you're new to CBD, R+R Medicinals suggests starting with their 500 or 1,000 milligram concentration or choosing their CBD Softgels instead. All R+R Medicinals CBD testing is conducted by SC Labs, Botanacor Labs, and AgriScience Labs.

Credit: cornbreadhemp.com

Best for Nighttime: Cornbread Hemp Whole Flower USDA Organic CBD Oil

Buy It
  • Type of CBD: Full-spectrum
  • Potency: 50 milligrams of CBD per 1 milliliter dropper
  • COA: Available online
  • Price: $$
  • Customer review: "Sometimes I have trouble getting to sleep and this stuff has really helped with that. It's just what I need to calm the brain."

Cornbread Hemp's Flower Only formula uses only the parts of the plant where CBD is found naturally, meaning the oil is not diluted with lower-grade parts of the hemp plant like the leaves, stems, and roots. Free of artificial flavorings and preservatives, this oil tincture is USDA organic, vegan, gluten-free, non-GMO, and third-party lab tested for purity by Kaycha Labs, Digipath Labs, and BlueLeaf Labs. Customers claim that it helps specifically with sleep and anxiety.

Credit: NuLeaf Naturals

Best Organic: NuLeaf Naturals Full-Spectrum CBD Oil

Buy It
  • Type of CBD: Full-spectrum
  • Potency: 30 milligrams of CBD per 1 milliliter dropper
  • COA: Available online
  • Price: $$
  • Customer review: "This CBD oil works great! I am so thankful for it. My pain level has gone down enormously."

NuLeaf Naturals produces high-quality cannabis products from its own hemp grown organically in Colorado. The company uses organic virgin hemp seed oil to maximize the health benefits without harsh solvents and other additives. NuLeaf Naturals offers a universal strength of 30 milligrams of CBD per 1 milliliter dropper in all of their products. You can then choose between bottles that range in size from 300 milligrams to 6,000 milligrams of CBD in total. Each NuLeaf Naturals product includes a batch number you can use to look up the independent lab test reports for that specific batch of CBD.

Best Taste: Charlotte's Web CBD Oil

Buy It
  • Type of CBD: Full-spectrum
  • Potency: 60 milligrams of CBD per 1 milliliter dropper
  • COA: Available online
  • Price: $$
  • Customer review: "This is the strongest CBD I've tried yet and I'm really happy with the results. Once a day in the morning is all I need [...]."

Those who want to maximize their CBD supplement routine can choose Charlotte's Web maximum strength oil, which offers 60 milligrams of CBD per serving. Best of all, this oil comes in three appealing flavors: Mint Chocolate, Lemon Twist, and Orange Blossom. This is a great CBD oil for supporting healthy sleep habits and managing stress. Charlotte's Web uses Eurofins Food Chemistry Testing to ensure the purity of its CBD.

Best Broad-Spectrum: Joy Organics Broad-Spectrum CBD Oil

Buy It
  • Type of CBD: Broad-spectrum
  • Potency: 15, 30, 45, or 75 milligrams of CBD per 1 milliliter dropper
  • COA: Available online
  • Price: $$
  • Customer review: "I take Joy Organics CBD oil just before bed each night and it helps quiet my mind and gives me a more sound sleep."

Joy Organics infuses broad-spectrum CBD oil in a blend of organic olive oil for a potent formula designed to melt away stress and help you relax at night. This USDA organic oil contains 0% THC, is cruelty-free and is certified by the U.S. Hemp Roundtable. It's available in four different strengths, including 45 and 75 milligrams of CBD per one milliliter dropper for a stronger dose. Joy Organics conducts both in-house testing and has all products tested by independent labs including Stillwater Laboratory, Pixis Labs, and Green Scientific Labs.

Methodology

There are multiple factors to consider when searching for the best CBD oil for you. Especially when comparing strong CBD oils, it's important to choose trusted CBD brands that offer transparency. The supplement industry is largely unregulated, so it's crucial to commit to brands that go the extra step to share product information publicly. 

Here are the primary factors we considered in making our list of CBD products.

Concentration

CBD products vary in concentration and potency. CBD oil strength is expressed as milligrams of CBD per container (typically 30 milliliter bottles) or per 1 milliliter dropper. Here's a general guideline to understanding the strengths of oil tinctures based on the milligrams of CBD they contain.

  • Average strength: 500–750 milligrams of CBD per 30 milliliters
  • Strong: 1,000–1,500 milligrams of CBD per 30 milliliters
  • Extra strength: 2,000+ milligrams of CBD per 30 milliliters

All of the CBD oils on our list contain at least 30 milligrams of CBD per one milliliter dropper.

Third-party lab test results

All credible CBD companies will share a certificate of analysis (COA) on their website. This is a record of third-party testing performed by independent organizations for every batch of CBD. It shares details from the lab test results about the extract's potency and precise cannabinoid composition and will confirm whether it is free of unwanted contaminants, such as pesticides or heavy metals. A CoA affirms that a CBD company has nothing to hide, so consider shopping elsewhere if it's not readily available.

Hemp sourcing

American-grown hemp must adhere to more stringent production laws than international crops, and organically-grown hemp is certified to be free from pesticides and artificial fertilizers. Pay attention to where a company sources its hemp, and consider it a red flag if this information isn't easy to find.

Finally, keep in mind that the FDA does not evaluate CBD products for safety or efficacy. Make sure you speak with your doctor before adding supplements of any form to your daily routine.

Price

To compare the cost and value of the strongest CBD tinctures, we divided price by the total amount of CBD for each bottle to find the cost per milligram of CBD. This helped us to determine and compare the value of each brand's high-concentration tinctures. Each one was then labeled using the following ranges:

$ = Under $0.05 per milligram of CBD
$$ = Between $0.06 and $0.10 per milligram of CBD
$$$ = Between $0.10 and $0.12 per milligram of CBD
$$$$ = Over $0.12 per milligram of CBD

Why does CBD potency matter?

Do high concentration CBD oils offer a real advantage over lower potency tinctures? Research shows that CBD oils may provide certain health benefits. These include reducing inflammation, providing temporary pain relief, and even easing the symptoms of anxiety.

The amount of CBD necessary to experience these benefits can vary person to person and can depend on factors including your size, metabolism, and tolerance for CBD. One study from 2019 measured the effects of CBD on patients in a psychiatric clinic who suffered from anxiety and poor sleep. The study involved 72 participants taking a daily dose of CBD and then reporting any changes to their anxiety or sleep on a monthly basis. The majority of the group took doses of 25 milligrams per day, while a few others with more severe symptoms were given doses of 50 or 75 milligrams per day. One patient was given a daily dose that gradually increased to 175 milligrams. A majority of patients, 79.2%, reported decreases in anxiety that lasted throughout the study. 66.7% of patients reported improved sleep, though these results fluctuated over the course of the study.

Significantly, the study's authors noted that CBD was well tolerated by all but three patients, and concluded that it "has a low overall risk with short term use." They did note, however, that more research is needed to establish if there are any risks associated with long-term use. saw improvements in both categories from CBD strengths in this range.

The best strategy for CBD beginners is to start with an average or lower-strength CBD oil (something between 15 and 30 milligrams per 1 milliliter dropper) and scale up until you determine what works for you. If you want a more substantial effect, you can scale up to the higher-strength CBD oils listed here.

Understanding full-spectrum vs. broad-spectrum vs. CBD isolate

Most CBD extracts today fall into one of three categories. Each offers a different concentration of beneficial cannabinoids and will have slightly different effects.

Full-spectrum hemp extract

Full-spectrum CBD extract is made from the entire hemp plant and contains the plant's full range of cannabinoids, terpenes, and flavonoids. These compounds work synergistically to maximize the benefits for your body in what's known as the entourage effect

Note that full spectrum CBD products are legally allowed to contain up to 0.3% of the psychoactive cannabinoid THC. This low concentration won't get you high, but it might still show up on a drug test.

Broad-spectrum hemp extract

Similar to full-spectrum, broad-spectrum CBD contains a wide range of hemp-derived cannabinoids and terpenes beyond CBD. The primary difference is that broad-spectrum CBD is processed further to remove THC content. These oils offer many of the benefits of full-spectrum products, without the THC.

CBD isolate

Also known as pure CBD, CBD isolate is distilled to remove all other cannabinoids and compounds extracted from the hemp plant. While this ensures the oil is 100% free of THC, it also eliminates the potential benefits of the entourage effect found in full-spectrum and broad-spectrum CBD oils.

Are there any side effects from taking too much CBD?

CBD can cause certain uncomfortable side effects, especially when taken at higher doses. These are typically mild but may include nausea, fatigue, dry mouth, diarrhea, reduced appetite, and irritability.

There are no universal guidelines for how much CBD oil is too much. Everyone responds a little differently to this natural plant compound, and factors like your body weight, metabolism, and body chemistry can affect its impact. 

As noted above, it's recommended that you start with a low dose, assess the effects, and gradually increase to higher concentrations of CBD until you achieve the desired results. Taking CBD could affect certain medications, such as the blood thinner coumadin. If you take prescription medications, it's best to speak with your doctor before starting CBD to rule out interaction concerns and determine what the best starting dose would be for your situation.

Lydia Noyes is a freelance writer specializing in health and wellness, food and farming, and environmental topics. When not working against a writing deadline, you can find Lydia outdoors where she attempts to bring order to her 33-acre hobby farm filled with fruit trees, heritage breed pigs, too many chickens to count, and an organic garden that somehow gets bigger every year.

This content is for informational purposes only and does not constitute medical advice; it is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition and before consuming or using any of the products mentioned on this site.

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