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Knowing what to trash and exactly when to do it will make the coziest room in your house healthier and more sleep-friendly.

Vacuuming the dust bunnies under your bed isn’t the only thing you need to do to maintain a healthy and hygienic bedroom. Hanging on to pillows, sheets, even your comfy slippers past their shelf life can aggravate allergies, lead to skin breakouts, and even set you up for falling or catching a bug. Do your body a favor and find out exactly when to let go of six common items everyone has in their bedroom—and the best options to replace them with.

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