Rare Disorders

These conditions may be infrequent, but that doesn't make them any less scary or puzzling. Causes can range from genetic abnormalities to certain diseases and infections.

Most Recent

MasterChef Junior Contestant Ben Watkins Died From Angiomatoid Fibrous Histiocytoma—Here's What That Is

MasterChef Junior Contestant Ben Watkins Died From Angiomatoid Fibrous Histiocytoma—Here's What That Is

Watkins died at 14 after battling this rare soft-tissue cancer for a year and a half.
What Is Stevens-Johnson Syndrome? This Rare Skin Disorder Can Make Your Skin Fall Off at the Touch

What Is Stevens-Johnson Syndrome? This Rare Disorder Can Make Skin Fall Off at the Touch

Meet two women who live with this rare condition, plus what doctors know about it.
This Model Lost Her Foot and Fingers to a Rare Condition, and It Taught Her to Love Her Body Even More

This Model Lost Her Foot and Fingers to a Rare Condition, and It Taught Her to Love Her Body Even More

Lyric Heard doesn't want to be treated differently from other models because of her disability.
Sister Wives Star Maddie Brown Brush’s Baby Daughter Undergoes Amputation Surgery

Sister Wives Star Maddie Brown Brush’s Baby Daughter Undergoes Amputation Surgery

The reality star previously revealed to PEOPLE that her daughter Evangalynn has a rare condition that causes limb malformation.
What Is Walking Corpse Disorder? Experts Explain This Rare Mental Illness

What Is Walking Corpse Disorder? Experts Explain This Rare Mental Illness

Medically known as Cotard delusion, this baffling mental disorder causes a person to believe they are dead.
My Constant Insomnia Turned Out to Be a Symptom of a Rare Disorder Called Hypophosphatasia

My Constant Insomnia Turned Out to Be a Symptom of a Rare Disorder Called Hypophosphatasia

After doctors couldn't figure out why she was suffering such terrible insomnia, Heather Barrow, 41, did her own research—and she learned she was born with a rare genetic disorder that also affected her mom and teenage daughter.

More Rare Disorders

47-Year-Old Woman Needs a Feeding Tube After Getting Mercury Poisoning From Skin-Lightening Cream

Woman Gets Mercury Poisoning From Using Skin-Lightening Cream, According to CDC

She reportedly used the cream twice a day for seven years.
This Woman's Urine Turned Purple—and That's Actually More Common Than You'd Think

This Woman's Urine Turned Purple—and That's Actually More Common Than You'd Think

But it's just as alarming as it sounds.
This Baby Born With His Brain Outside of His Skull Is the First to Survive the Rare Condition

Miracle Baby Born With Brain Outside of Skull Believed to Be First to Survive Rare Condition

This Girl's Blood and Skin Turned Blue After Using a Topical Anesthetic—Here's Why

What is Methemoglobinemia? What to Know About the Rare Disorder That Turned One Woman’s Blood Blue

The Large, Painful Sores on This Man's Hands Were Caused By An Extremely Rare Inflammatory Disease

The Large, Painful Sores on This Man's Hands Were Caused By An Extremely Rare Inflammatory Disease

Woman Posts Important Warning After Curling Little Sister's Hair Triggers Seizure Symptoms

Woman Posts Important Warning After Curling Little Sister's Hair Triggers Seizure Symptoms

Two-Year-Old Born Battling Rare Prune Belly Syndrome Needs a New Kidney

Two-year-old will receive a kidney from a woman who had been following his story on social media.

All Rare Disorders

This Woman Woke Up With a Rare Condition That Makes Her Unable to Hear Men’s Voices

This Woman Woke Up With a Rare Condition That Makes Her Unable to Hear Men’s Voices

16-Month-Old Boy Needs Surgery for Rare Condition that Caused His Tongue to Double in Size

16-Month-Old Boy Needs Surgery for Rare Condition that Caused His Tongue to Double in Size

This Woman Woke Up With a British Accent. Here's What to Know About Foreign Accent Syndrome

This Woman Woke Up With a British Accent. Here's What to Know About Foreign Accent Syndrome

Did a British Teen Die After Eating Her Own Hair? Here's What to Know About a Rare Condition Called "Rapunzel Syndrome"

Did a British Teen Die After Eating Her Own Hair? Here's What to Know About a Rare Condition Called "Rapunzel Syndrome"

Rare Disorder Causes Severe Head Rushes

Rare Disorder Causes Severe Head Rushes

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