3 Cold-Season Meds That Can Affect Your Vagina

What you need to know about these medications that may ease your runny nose and sore throat—but mess with your vaginal health, and sex.

As temperatures drop, the number of people sneezing, sniffling, and coughing rises. As a result, the odds are good that more people will be taking cold medicine (or meds that treat related conditions, such as the flu, strep throat, or a sinus infection) to get rid of these symptoms.

While over-the-counter or prescription cold fighters do a decent job of treating your condition, they also have the power to mess with other parts of the body—including your vagina.

"Some [people] take these meds and have absolutely no problem at all," stated Alyssa Dweck, MD, a New York-based ob-gyn and co-author of The Complete A to Z for Your V. Other people notice vaginal changes that affect sexual pleasure and increase their risk of infection. These three commonly used anti-cold meds prepare you for the cold and flu season but can also have these effects on your vagina.


Antihistamines are the main ingredient in allergy meds, so they are also found in many cold formulas. They dehydrate the mucus membranes in your nasal passages, which puts an end to symptoms like a runny nose, watery eyes, and sneezing. However, they can also dry up the mucus membranes in your vagina as well. "Antihistamines can cause the blood vessels to constrict, so there's less blood flow and therefore fewer secretions throughout the body," Dr. Dweck told Health.

Dr. Dweck stated that it's not uncommon for people with cold symptoms to complain about vaginal dryness caused by an antihistamine medication they've been instructed to take at least once a day. The dryness isn't permanent, of course, but it can be uncomfortable. It can also cause difficulty during sex. If you do have intercourse, you may end up with small abrasions.

If vaginal dryness is a problem, you have options. Dr. Dweck encouraged people to talk to their healthcare provider about switching from an oral antihistamine to a nasal spray, "whether that's a steroid spray or something just made with saline," Dr. Dweck stated. "This might help because it works more locally rather than drying things up all over." Using lubricant in place of your own natural wetness is also an option.


As if coming down with strep throat isn't bad enough, the antibiotic your doctor might prescribe to cure it can set you up for a vaginal yeast infection. "Antibiotics alter the very delicate balance of normal bacteria found in the vagina," Dr. Dweck explained to Health. "When that balance is off, the pH can change, and you can become more prone to [an overgrowth of] yeast."

It's unclear why antibiotics cause some people to develop a yeast infection while others never have any issues. But taking antibiotics on a long-term basis—as opposed to a short course for something like a UTI—may have more of an effect on the balance of vaginal flora, she stated.

If you are prone to yeast infections, talk to your healthcare provider about taking an oral probiotic and using an anti-yeast medication (like Monistat) while you are on antibiotics, suggested Dr. Dweck. If you do develop yeast infection symptoms such as itching, burning, and a thick discharge, take comfort in knowing that the condition is treatable. "Yeast is usually pretty easily treated and cured," Dr. Dweck told Health.


Similar to antihistamines, decongestants may also dry up a runny nose by narrowing blood vessels. While this ingredient in many popular cold medications does a solid job of dehydrating your nasal passages, it also removes moisture from the vaginal area as well, stated Dr. Dweck.

To keep your dry vagina from feeling uncomfortable or temporarily ruining your sex life, visit the pharmacy to pick up your decongestant of choice, and also pick up a lubricant while you're at it. Another option is to not take a decongestant drug and try to clear your nasal passages with natural decongestant remedies, such as drinking hot liquids and taking a steamy shower.

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