In a recent study, women who took 80 milligrams of iron daily had a 48% drop in fatigue. They were otherwise healthy people whose iron levels were on the lower end of normal. If you're tired all the time, ask your doc to check your levels.

By News & Views
November 22, 2012
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Medications aren't the only treatment for restless legs. "Every time someone comes into my clinic complaining of something that may sound like restless legs, we check their iron," says Dr. Tagliati, who has received speaking fees from a company that makes RLS drugs. "If they're low, we treat it with supplementation." Restoring iron levels in the body also can help restore dopamine in the brain, experts believe, which may help reduce RLS symptoms. Folate and magnesium supplements may also relieve RLS symptoms.
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In a recent study, women who took 80 milligrams of iron daily had a 48% drop in fatigue. They were otherwise healthy people whose iron levels were on the lower end of normal. If you're tired all the time, ask your doc to check your levels. (Note: too much iron can be toxic, though. So consult an MD before adding it as a supplement.)