Laurence Moon Syndrome

Synonyms

• Adipogenital-Retinitis Pigmentosa Syndrome
• Laurence Syndrome
• LM Syndrome

Disorder Subdivisions

• None

General Discussion

Laurence-Moon Syndrome is a rare inherited disorder characterized by diminished hormone production by the testes or ovaries (hypogonadism), progressive loss of vision (retinitis pigmentosa), mental retardation, and paralysis of the legs and lower part of the body accompanied by involuntary muscle contractions (spastic paraplegia). Confusion exists in the medical literature regarding the difference between Laurence-Moon Syndrome and Bardet-Biedl Syndrome. Some researchers believe that Bardet-Biedl Syndrome is a subdivision of Laurence-Moon Syndrome which they term "Laurence-Moon-Biedl Syndrome."

Resources

National Association for Visually Handicapped

22 West 21st Street

New York, NY 10010

USA

Tel: (212)889-3141

Fax: (212)727-2931

Email: staff@navh.org

Internet: http://www.navh.org



March of Dimes Birth Defects Foundation

1275 Mamaroneck Avenue

White Plains, NY 10605

Tel: (914)428-7100

Fax: (914)997-4763

Tel: (888)663-4637

Email: Askus@marchofdimes.com

Internet: http://www.marchofdimes.com



The Arc (a national organization on mental retardation)

1010 Wayne Ave

Suite 650

Silver Spring, MD 20910

Tel: (301)565-3842

Fax: (301)565-3843

Tel: (800)433-5255

TDD: (817)277-0553

Email: info@thearc.org

Internet: http://www.thearc.org/



National Association for Parents of Children with Visual Impairments (NAPVI)

P.O. Box 317

Watertown, MA 02472

Tel: (617)972-7441

Fax: (617)972-7444

Tel: (800)562-6265

Email: napvi@perkins.org

Internet: http://www.napvi.org



American Council of the Blind, Inc.

1155 15th Street

Suite 1004

Washington, DC 20005

Tel: (202)467-5081

Fax: (202)467-5085

Tel: (800)424-8666

Internet: http://www.acb.org



American Foundation for the Blind

11 Penn Plaza

Suite 300

New York, NY 10001

Tel: (212)502-7600

Fax: (212)502-7777

Tel: (800)232-5463

TDD: (212)502-7662

Email: afbinfo@afb.org

Internet: http://www.afb.org



Blind Children's Fund

311 W. Broadway

Suite 1

Mt. Pleasant, MI 48858

Tel: (989)779-9966

Fax: (989)779-0015

Email: bcf@blindchildrensfund.org

Internet: http://www.blindchildrensfund.org



Council of Families with Visual Impairment

1155 15th St. NW

Suite 1004

Washington, DC 20005

Tel: (202)465-5081

Fax: (202)465-5085

Email: info@acb.org

Internet: http://www.acb.org/



Prevent Blindness America

211 West Wacker Drive

Suite 1700

Chicago, IL 60606

Tel: (312)363-6001

Fax: (312)363-6052

Tel: (800)331-2020

Email: info@preventblindness.org

Internet: http://www.preventblindness.org



National Institute of Neurological Disorders and Stroke (NINDS)

31 Center Drive

8A07

Bethesda, MD 20892-2540

Tel: (301)496-5751

Fax: (301)402-2186

Tel: (800)352-9424

Email: braininfo@ninds.nih.gov

Internet: http://www.ninds.nih.gov/



MUMS (Mothers United for Moral Support, Inc) National Parent-to-Parent Network

150 Custer Court

Green Bay, WI 54301-1243

USA

Tel: (920)336-5333

Fax: (920)339-0995

Tel: (877)336-5333

Email: mums@netnet.net

Internet: http://www.netnet.net/mums/



Perkins School for the Blind

175 North Beacon St.

Watertown, MA 02472

Tel: (617)924-3434

Fax: (617)926-2027

Email: Info@Perkins.org

Internet: http://www.Perkins.org

For a Complete Report

This is an abstract of a report from the National Organization for Rare Disorders, Inc. ® (NORD). A copy of the complete report can be obtained for a small fee by visiting the NORD website. The complete report contains additional information including symptoms, causes, affected population, related disorders, standard and investigational treatments (if available), and references from medical literature. For a full-text version of this topic, see http://www.rarediseases.org/search/rdblist.html

The information provided in this report is not intended for diagnostic purposes. It is provided for informational purposes only. NORD recommends that affected individuals seek the advice or counsel of their own personal physicians.

It is possible that the title of this topic is not the name you selected. Please check the Synonyms listing to find the alternate name(s) and Disorder Subdivision(s) covered by this report

This disease entry is based upon medical information available through the date at the end of the topic. Since NORD's resources are limited, it is not possible to keep every entry in the Rare Disease Database completely current and accurate. Please check with the agencies listed in the Resources section for the most current information about this disorder.

For additional information and assistance about rare disorders, please contact the National Organization for Rare Disorders at P.O. Box 1968, Danbury, CT 06813-1968; phone (203) 744-0100; web site www.rarediseases.org or email orphan@rarediseases.org

Last Updated:  8/7/2007

Copyright  1986, 1987, 1989, 1990, 1993, 1997, 1999, 2007 National Organization for Rare Disorders, Inc.