Fetal Valproate Syndrome

Synonyms

• Dalpro, Fetal Effects From
• Depakene, Fetal Effects From
• Depakote Sprinkle, Fetal Effects From
• Depakote, Fetal Effects From
• Divalproex, Fetal Effects From
• Epival, Fetal Effects From
• Myproic Acid, Fetal Effects From
• Valproic Acid, Fetal Effects From
• Fetal Anti-Convulsive Syndrome

Disorder Subdivisions

• None

General Discussion

Fetal Valproate Syndrome is a rare congenital disorder caused by exposure of the fetus to valproic acid (dalpro, depakene, depakote, depakote sprinkle, divalproex, epival, myproic acid) during the first three months of pregnancy. Valproic acid is an anticonvulsant drug used to control certain types of seizures in the treatment of epilepsy. A small percentage of pregnant women who take this medication can have a child with Fetal Valproate Syndrome. The exact prevalence of this condition remains to be established. Symptoms of this disorder may include spina bifida, distinctive facial features, and other musculoskeletal abnormalities.

Resources

Spina Bifida Association of America

4590 MacArthur Boulevard NW

Suite 250

Washington, DC 20007-4226

Tel: (202)944-3285

Fax: (202)944-3295

Tel: (800)621-3141

Email: sbaa@sbaa.org

Internet: http://www.sbaa.org



International Federation for Spina Bifida and Hydrocephalus

Cellebroersstraat 16

Brussels, B1000

Belgium

Tel: +32 (0)2 502 0413

Fax: +32 (0)2 502 1129

Email: info@ifglobal.org

Internet: http://www.ifglobal.org



Spina Bifida and Hydrocephalus Canada

Suite 647-167 av. Lombard Avenue

Winnipeg

MB

R3B 0V3

Canada

Tel: 204-925-3650

Fax: 204-925-3654

Tel: 800-565-9488

Email: info@sbhac.ca

Internet: http://www.sbhac.ca



National Fetal AntiConvulsant Syndrome Association

P.O. Box 7416

Annan, Intl DG12 5ET

United Kingdom

Tel: 01 461 206 870

Fax: 01 461 206 870

Email: facsline3@aol.com

Internet: http://www.facsline.org



Organisation For Anti-Convulsant Syndrome

PO Box 772

Pilling

Preston, Intl PR3 6WW

UK

Tel: 01253 790022

Fax: 01253 790022

Email: janet.oacs@o2.co.uk or tegs78@ntlworld.com

Internet: http://www.oacs-uk.co.uk/



Genetic and Rare Diseases (GARD) Information Center

PO Box 8126

Gaithersburg, MD 20898-8126

Tel: (301)251-4925

Fax: (301)251-4911

Tel: (888)205-2311

TDD: (888)205-3223

Email: http://rarediseases.info.nih.gov/GARD/EmailForm.aspx

Internet: http://rarediseases.info.nih.gov/GARD

For a Complete Report

This is an abstract of a report from the National Organization for Rare Disorders, Inc. ® (NORD). A copy of the complete report can be obtained for a small fee by visiting the NORD website. The complete report contains additional information including symptoms, causes, affected population, related disorders, standard and investigational treatments (if available), and references from medical literature. For a full-text version of this topic, see http://www.rarediseases.org/search/rdblist.html

The information provided in this report is not intended for diagnostic purposes. It is provided for informational purposes only. NORD recommends that affected individuals seek the advice or counsel of their own personal physicians.

It is possible that the title of this topic is not the name you selected. Please check the Synonyms listing to find the alternate name(s) and Disorder Subdivision(s) covered by this report

This disease entry is based upon medical information available through the date at the end of the topic. Since NORD's resources are limited, it is not possible to keep every entry in the Rare Disease Database completely current and accurate. Please check with the agencies listed in the Resources section for the most current information about this disorder.

For additional information and assistance about rare disorders, please contact the National Organization for Rare Disorders at P.O. Box 1968, Danbury, CT 06813-1968; phone (203) 744-0100; web site www.rarediseases.org or email orphan@rarediseases.org

Last Updated:  4/25/2008

Copyright  1994, 2003 National Organization for Rare Disorders, Inc.