13 Drugs That Can Make You Gain Weight

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Zyprexa (olanzapine)

Atypical antipsychotics, such as Zyprexa and Clozaril (clozapine), can pile on the pounds. A 2005 study found that 30% of people on Zyprexa gained 7% or more of their body weight within 18 months.

These drugs, used for schizophrenia and bipolar disorder, have potent antihistamine activity and inhibit serotonin, which may trigger weight gain.

The diabetes drug metformin may help keep weight off, as can switching to weight-neutral antipsychotics like Geodon (ziprasidone) and Abilify (aripiprazole).

Next: Deltasone (prednisone)

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