8 Types of Cancer Linked to Rheumatoid Arthritis

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Lymphoma linked to TNF inhibitors  

There have been two cases of RA patients developing a rare and fatal type of non-Hodgkin's lymphoma called hepatosplenic T-cell lymphoma while taking Humira (adalimumab), a TNF inhibitor.

The FDA also reported 40 other cases in patients (mostly adolescents) with Crohn's disease and ulcerative colitis who were taking Humira, as well as other TNF inhibitors and immunosuppressants—all of which are also prescribed for RA. Although the agency says it is difficult to know the risk of these drugs because the conditions on their own are associated with increased lymphoma risk, it says the risks and benefits should be "carefully weighed when prescribing these drugs to children and young adults."

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