5 Steps to Take If Heartburn Won't Quit

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When acid reflux persists

By Karen Pallarito

Proton pump inhibitors, or PPIs, curb stomach acid production, keeping gastric juice from backing up into the esophagus and causing heartburn.

But they don’t always work—sometimes because heartburn has been misdiagnosed. Even when PPIs do work, up to 40% of people can still have breakthrough symptoms from time to time.

Fortunately, there are things you can do to prevent and minimize breakthrough symptoms.

Next: Make sure you're taking medication correctly