Sexual Health:Sexually Transmitted Diseases

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How HPV Causes Cervical Cancer and Abnormal Pap Smears


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Human papillomavirus, or HPV, is so common that one out of every two sexually active adults has been infected with one or more of the approximately 100 types of HPV, only 30 of which are transmitted sexually. Most of these are benign, but some can cause genital warts, while others can cause cervical cancer—a disease that can be halted in its very early stages by a gentle, painless scraping of the cervix known as a Pap smear, generally recommended annually.


What is an abnormal Pap test?
A Pap test, or Pap smear, is part of a woman’s routine physical exam. It is the best way to prevent cervical cancer, because it can find cells on your cervix that could turn into cancer. The cervix is the lower part of the uterus that opens into the vagina.

When your doctor says that your Pap test was "abnormal," it means that the test found some cells on your cervix that do not look normal. It does not mean that you have cancer. In fact, the chances that you have cancer are very small.

What causes an abnormal Pap test?
Most of the time, abnormal cell changes on the cervix are caused by certain types of human papillomavirus, or HPV. HPV is a sexually transmitted disease. Usually these cell changes go away on their own. But certain types of HPV have been linked to cervical cancer. That’s why it’s important for women to have regular Pap tests. It takes many years for cell changes in the cervix to turn into cancer.

Sometimes cell changes in the cervix are due to other types of infection, such as infections caused by bacteria or yeast. These types of cell changes can be treated. In women who have been through menopause, a Pap test may find cell changes that are just the result of getting older.
Last Updated: January 12, 2007 See Full Credits Disclaimer


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Last Updated: May 10, 2008


Last Updated: January 12, 2007
Author:
Shannon Erstad, MBA/MPH
Medical Review:
Joy Melnikow, MD, MPH - Family Medicine

Barbara S. Apgar, MD, MS - Family Medicine, Women's Health

Ross Berkowitz, MD - Obstetrics and Gynecology


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