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Melatonin and Sleep Problems: When This Hormone Might Work for You


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When produced naturally in your brain, melatonin helps your body distinguish between day and night; it's what makes you tired when it gets dark, and wakes you when the sun comes up (or when a bright light is turned on in your bedroom).

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If something hinders this process, like changing time zones or developing a sleep rhythm disorder, small amounts of synthetic melatonin, sold over-the-counter, may help you readjust to a normal sleep schedule.

Melatonin won't work for every case of insomnia or sleeping problems, though. "Your body has to be ready for sleep for melatonin to work," says David Rapoport, MD, medical director of the New York University Sleep Disorders Clinic. "So for those people who have insomnia because they just don't get sleepy—we call this hyperarousal—melatonin won't do them much good."

Certain groups of people that lack natural melatonin, blind people or older adults, for example, may benefit from melatonin. But overall, its safety and effectiveness has not been thoroughly studied. Large doses can cause daytime sleepiness and further sleep disruptions, and may interfere with women's ovulation. Read the safety information below and talk to your doctor before considering melatonin or its prescription-strength counterpart, Rozerem.

The following is from our A-Z Health Library:

What is melatonin?
Melatonin is a hormone produced in the pineal gland (see an illustration here), a small gland in the brain, that helps regulate sleep and wake cycles. Very small amounts of melatonin are found in foods such as meats, grains, fruits, and vegetables. It is also available as a dietary supplement, though it has no known nutritional value.

What does natural melatonin do in the body?
Your body has its own internal clock that helps regulate your natural cycle of sleeping and waking hours (or circadian rhythm) in part by controlling the production of melatonin. Normally, melatonin levels begin to rise in the mid- to late evening, remain high for most of the night, and then decline in the early morning hours.

Natural melatonin production is partly affected by light. During the shorter days of the winter months, melatonin production may start earlier or, more often, later. This change can lead to symptoms of seasonal affective disorder (SAD), or winter depression.

Natural melatonin levels decline gradually with age. Some older adults produce very small amounts of melatonin or none at all.

Last Updated: July 28, 2008 See Full Credits Disclaimer
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Last Updated: May 03, 2008


Last Updated: July 28, 2008
Author:
Jeannette Curtis
Medical Review:
Kathleen Romito, MD - Family Medicine

Alfred Lewy, MD, PhD - Psychiatry


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