Heart Disease:Statins and Other Drugs

Calcium Channel Blockers Can Treat Coronary Artery Disease


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Examples

Generic NameBrand Name
Amlodipine besylateNorvasc
Diltiazem hydrochlorideCardizem, Dilacor XR, Taztia, Tiazac
FelodipinePlendil
IsradipineDynaCirc
Nicardipine hydrochlorideCardene
NifedipineProcardia XL
NisoldipineSular
Verapamil hydrochlorideCalan SR, Isoptin SR

How they work
Calcium channel blockers help treat coronary artery disease by:

  • Increasing blood flow to the heart muscle by expanding (dilating) the coronary arteries.
  • Possibly helping to prevent a spasm of the coronary arteries.
  • Lowering blood pressure and the workload on the heart, which allows the heart muscle to function with less oxygen and blood flow.
  • Sometimes slowing a rapid heart rate and controlling irregular heart rhythms.
Why they are used
Calcium channel blockers are commonly used in people with coronary artery disease who have one or more of the following conditions:

  • Stable angina
  • Episodes of spasm affecting the coronary arteries
  • Inability to take beta-blockers, or beta-blockers are ineffective in controlling a rapid heart rhythm


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Last Updated: April 28, 2008


Last Updated: January 8, 2008
Author:
Robin Parks, MS
Medical Review:
Caroline S. Rhoads, MD - Internal Medicine

Robert A. Kloner, MD, PhD - Cardiology

Ruth Schneider, MPH, RD - Diet and Nutrition


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