The drug has benefits, namely an ability to promote weight loss in some patients. It also has potential risks and side effects, including nausea. The Food and Drug Administration (FDA) has reported a possible link between Byetta and cases of acute pancreatitis, which is an inflammation of the pancreas that requires immediate medical attention.
While on Byetta
I developed pancreatitis Watch video
More about Byetta
Approved by the FDA in 2005, Byetta is the first in a new class of drug called the incretin mimetics.
The drug is administered with a pen injector twice a day into the abdomen, upper thigh, or upper arm. Although it's not a substitute for insulin, it may be taken with metformin, a sulfonylurea, or a thiazolidinedione.
How it works
Incretin mimetics act like (mimic) the natural hormones in your body that lower blood sugar. These hormones are called incretins. Exenatide:
Exenatide can be used when metformin or sulfonylurea drugs are not working to control blood sugar. You may take exenatide by itself or with these oral drugs. You most likely will not use exenatide if you are using insulin.
Incretin mimetics act like (mimic) the natural hormones in your body that lower blood sugar. These hormones are called incretins. Exenatide:
- Allows your pancreas to release insulin. This drug lowers blood sugar levels only when they rise too high.
- Prevents the pancreas from giving out glucagon. Glucagon is a hormone that causes the liver to release its stored sugar into the bloodstream.
- Helps to slow the rate at which your stomach empties after eating. This may make you feel less hungry and more satisfied after a meal.
Exenatide can be used when metformin or sulfonylurea drugs are not working to control blood sugar. You may take exenatide by itself or with these oral drugs. You most likely will not use exenatide if you are using insulin.
Last Updated: July 11, 2006 
