Giuliana Rancic: How I Got Through the Tough Stuff

Infertility. Miscarriage. Breast cancer. How did Giuliana Rancic get through it all and emerge with her health and baby dreams intact?

Life is good, I gotta be honest," laughs Giuliana Rancic. Shes in her apartment in Chicago with her husband, Bill. And whos napping in his room? Their baby boy, Edward Duke. "Im in baby heaven," says the Italian-born TV host and fashion designer, sounding surprisingly calm considering that one year ago, after four years of struggling to conceive, she got the devastating news that she had breast cancer.

Viewers of the couples hit Style Network show Giuliana & Bill know the story well: Giuliana went through three IVFs (one she miscarried; one didnt take), and then, at 36, was diagnosed with cancer. She had a double mastectomy. Unable to carry the embryos from her third IVF (due to her cancer medication), she enlisted a gestational surrogate, who gave birth to their son on August 29. Come November, after a few months of baby-bonding, its back to work.

Jim Wright
On November 12, Giuliana will return to E! News with a new co-anchor, Terrence Jenkins. In addition to her co-hosting gig on E!'s Fashion Police, she has just launched her G by Giuliana Rancic collection on HSN, and will host NBC's spring show Ready for Love with Bill. Now, she tells Health what she's learned about staying positive when your world turns upside down.

Congratulations on Duke! Whats your favorite thing about him?
I love when I feed him in the middle of the night. Those moments are incredible, when its so quiet and theres just a little bit of a light on, just looking at his little face.

The road to baby was a tough one for you. Youve said you were blindsided by how difficult it was.
It was a big shock! I always say how I chased my career instead of chasing guys. And everybody was patting me on the back. No one ever told me, "Oh, by the way, your eggs change when you reach a certain age." I didnt think 35 was old! So when the doctor said, "Its not as easy as you thought it would be," it was a real blow. Because I felt so young. I mean, this is a girl who was running six miles a day, and eating healthy, so how can you tell me that Im not healthy in that department?

So would you have done anything differently?
I dont think I wouldve frozen my eggs. A lot of people throw that out there, like, "Oh, just freeze your eggs." That is major. Its surgery! As a 25-year-old making not a lot of money, youre not just going to go through all that and freeze your eggs.

Were you ever frustrated to see other women getting pregnant?
My first IVF I did get pregnant—that was the miscarriage. But the second one, I did not get pregnant, and that was the biggest kick in the stomach, because I just could not believe you go through so much to get those eggs and put them in, and when the doctor calls you, to hear, "Oh, sorry, it didnt work." That was the most shocking. I would go, "Im a good person, and I could give someone the greatest life of all, but yet I cant get pregnant." And then you watch these TV shows, 16 and Pregnant, and these girls who want nothing to do with their babies are pregnant. And youre going, what? None of that made sense to me.

Had you known what was coming, would you have chosen to keep any of this private?
Had you given me a crystal ball when we were signing on to do the reality show that said, "This is whats coming up, do you want to do it?" I wouldve said absolutely not. You couldnt pay me enough. But, looking back, Im so happy that I did do it. As I would question God, "Why are you doing this to me, why me?" I think God knew I was a loud-mouthed Italian girl who would get out and share my story, not tuck it under a rug.

After finding your cancer, did you know what your next steps would be?
No way, are you kidding? I was shell-shocked. I thought I was going to die. I didnt know that if you find breast cancer early enough, you have a 98 percent survival rate. I went to work right after finding out and did E! News. I recently watched that episode and I dont know how I pulled it off. Afterward, I ran into my dressing room and started hysterically crying. Bill was really the one who had to pick me up off the floor and say, "Hey, were making a plan here." He took over.

Jim Wright
You seem to display such grace under pressure. What is your secret?
Focus on the positive. Whenever I was so sad, when I was on the floor kicking and screaming and crying, the best way I could pull out of it was when I would remind myself: Even with this happening, youre still better off than a lot of people. For me, it was saying, "Yes, I have breast cancer. Yes, I had to have a double mastectomy." But, you know what? Thank God Im going to a good doctor. Im so fortunate I found it early. Im so fortunate to have Bill. Im so fortunate that I have a boss who understands.

What is your cancer prognosis right now?
As of this week, Im a one-year survivor! I get checked every three months, and Im looking good.

Where do you feel your absolute happiest?
Taking a long walk on the lakefront of Chicago with my husband and my baby boy.

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Amy Spencer
Last Updated: November 01, 2012

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