Everybody feels sad once in a while. Depression, on the other hand, is a complex condition characterized by profound sadness, lethargy, feelings of worthlessness, and a loss of interest in social activities. About 15 million people in the U.S. are diagnosed with clinical depression each year.

When Sight and Hearing Fail

Read about what can be done to prevent the depression that often follows

Choosing the Right Antidepressant

Why what works for others may not work for you

Vagus Nerve Stimulation Relieved Her Depression

A mother of three lost a decade to mental illness. Now she is smiling again

How Exercise May Boost Your Mood

The research is mixed, but many depression sufferers swear by it

Take the Depression Quiz

How good is your ability to recognize the symptoms of depression? Take our quiz to find out if someone has depression, why they may be susceptible to this mood disorder, and what they should do to turn it around.

Why I Don't Blame Myself for Depression

Depression is very isolating. You just don't talk about it in the same way you would if you broke a foot and were going to the hospital.